Tracing diseases in blood via exosomes
Novel integrated platform ExoPheno for the discovery and profiling of exosome phenotypes in diseases.
WHAT WE CHARACTERIZE
Exosomes and other extracellular vesicles are heterogeneous vesicles naturally secreted by all living cells. Their cargo contain molecular information (such as proteins, nucleic acids, lipids and metabolites) which is protected from enzymatic destruction. They are found in all biofluids, including blood. Exosomes from diseased tissue are perfect circulating snapshots of disease activity.
HOW WE CHARACTERIZE
Novel exosome charaterisation platform ExoPheno
ExoPheno™ characterizes disease-specific exosomes in several ways: it quantifies them, measures their relative expression of epitopes and analyses their cargo. Highly pre-selected intact exosomes are isolated and processed for deep discovery of biomarkers and druggable targets. Proprietary integrated technologies consist of immunocapture-and-release (for discovery) and novel nanoelectronics systems (for validation).
Supporting world-class research