Tracing diseases in blood via exosomes
Novel multi-omics exosome characterisation platform ExoPheno enabling the discovery and profiling of exosome phenotypes in diseases.
WHAT WE CHARACTERISE
Disease-specific exosomes in blood
Exosomes, also known as Extracellular Vesicles, have been shown to reflect the state of their cellular sources, transporting specific ‘-omics’ information (DNA, RNA, proteins, lipids and metabolites) either locally or to distant sites via the circulatory system, including blood.
Exosomes from diseased tissue are dynamic circulating snapshots of disease activity and can be analysed non-invasively with a blood draw.
HOW WE CHARACTERISE
Novel exosome characterisation platform ExoPheno
ExoPheno™ characterises the multi-omics cargo of exosomes in blood from a selected tissue of origin. It enables the creation of next generation liquid biopsy blood tests.
It consists of proprietary and patented technologies, which integrate wet lab (validated exosome tissue-of-origin markers, adaptative linker cleavage, pre-analytical multi-omics sequencing workflow and ultrasensitive exosome marker detection systems) and dry lab analysis via machine learning.
Supporting world-class research